BIOS Family Study

The Bipolar Offspring Family Study (BIOS) is a longitudinal study that has been following children and their families for the past 15 years.  The study is interested in learning about the early signs of bipolar disorder.  The study was recently renewed for 5 more years.  This new phase is called BIOS BEES and is currently recruiting participants.


Purpose: BEES seeks to identify demographic, familial, neural circuitry, and environmental factors that serve as predictors of psychopathology and resilience.

Who can participate:

  • youths between 8 and 16 years who are
  • diagnosed with bipolar and have
  • a parent diagnosed with bipolar disorder            

What does the study involve:

  • 2 assessments; 1 at intake and 1 at a 2-year follow-up
  • questionnaires and interviews about mood & emotion (1-2 hours)
  • child completing 2 MRI scans (about 6 hours with scan taking 1 hour); 1 at intake and 1 at 2-year follow-up

If you are interested in hearing more about this study and would like to see if you are eligible, please call Kelly Monk at (412) 246-5796 or Email


BIOS Newsletter

Volume 1, Issue 1